I'm going to repeat a posting that I found on Fishing Journal because I think it's such a great cause.
Ever hear of Casting for Recovery? If not, they are a non-profit organization that teaches women that are recovering from cancer how to fly fish. Like most non-profits, they fund themselves with donations. What is unique about CfR is that they take not just monetary donations but donations of the fly variety. They have a list of flies that they are looking for to distribute to the women that the help.
So if your a tier, why not send them a dozen or so flies? I know that I am.